Ehlers Danlos Syndrome (EDS)
What is Ehlers Danlos Syndrome?
The Ehlers-Danlos syndromes (EDS) are a group of 13 heritable connective tissue disorders that are frequently characterized by:
The conditions are thought to be caused by genetic changes that affect connective tissue; however, there are different theories as to how EDS is caused.
Because the hyper-mobile subtype is the most common, and it is the only subtype for which a mutation has not been conclusively identified, diagnosis at this moment is still based on clinical symptoms and findings; however, that is likely to change soon given the Norris lab has recently identified a genetic mutation called KLK15 that they believe may be responsible for some hEDS.
Here's the checklist for hEDS
How can EDS be treated?
The Ehlers-Danlos syndromes (EDS) are a group of 13 heritable connective tissue disorders that are frequently characterized by:
- Flexible joints
- Pale skin & veins
- Stretchy, fragile skin
- Tissue fragility with poor wound healing
- Easy bruising
- Hypermobile (most common)
- Classical
- Vascular
- Periodontal
- Kyphoscolitoic
- Spondylodysplastic Ehlers-Danlos Syndrome (spEDS)
- Brittle Cornea Syndrome
- Arthrochalasia Ehlers-Danlos Syndrome (aEDS)
- Musculocontractural Ehlers-Danlos Syndrome (mcEDS)
- Classical-Like EDS
- Dermatosparaxis Ehlers-Danlos Syndrome (dEDS)
- Myopathic
- Cardiac-Vulvular
The conditions are thought to be caused by genetic changes that affect connective tissue; however, there are different theories as to how EDS is caused.
- Specific genetic mutations
- RCCX Theory
- MCAS or a MCAS-degranulating, post-viral event like COVID
Because the hyper-mobile subtype is the most common, and it is the only subtype for which a mutation has not been conclusively identified, diagnosis at this moment is still based on clinical symptoms and findings; however, that is likely to change soon given the Norris lab has recently identified a genetic mutation called KLK15 that they believe may be responsible for some hEDS.
Here's the checklist for hEDS
How can EDS be treated?
- Dr. Bluestein's Holistic Approach
- Dr. Zingman's Prism approach
- Prolotherapy, PRP and Regenerative Medicine Treatment for EDS
- The Muldowney Protocol for PT with EDS
- What is EDS? by the Ehlers Danlos Society
- The link between EDS, MCAS & POTS by Dr. Weinstock, a GI
